![]() He says he feels very bad when it happens. He doesn't try to move for a minute or two says he feels weak, and sometimes cold. Lately, he has allowed himself to laugh more easily, but when he laughs "too much", he suddenly curls up in a fetal position, and usually has mild tremors, or shaking. He does appear to have "adrenaline rushes" while trying to fall asleep. He takes cortisone daily for secondary adrenal insufficiency. He has POTS, or at least, severe orthostatic hypotension with tachycardia, and also hypopituitarism. After that, he tried to hold back his laughter didn't want to anger his dad. He didn't seem to know or care that he was laughing louder than everyone else, until one night when his dad yelled at him to stop. At first I thought it was a behavioral thing, since he used to laugh really loudly until he was about seven years old. For the last five or six years, I've noticed he tries to suppress his laughter. He does not have a diagnosis of cataplexy, and definitely not narcolepsy. Does anyone know if laughter is a trigger for a cataplectic event? I've been trying to figure out why my son suddenly becomes so unusually weak after a couple of minutes of laughing. (8,9,11,12) Its incidence has been estimated to be about 0.74 per 100,000 person-years for narcolepsy with.Hi! Actually, I was just going to post a question about cataplexy. (8,12) Reports in the United States estimate a prevalence of population, whereas the prevalence in Japan is considerably higher (about 1 per 600 population) and in Israel it is much lower (about 1 per 500,000 population). (8) Narcolepsy appears throughout the world in every racial and ethnic group, but prevalence rates vary. (11)Īlthough the origins of narcolepsy are still not well known, clinical understanding of the neurologic dysfunction that underlies narcolepsy as well as treatment options have increased markedly in the last decade.Īccording to the National Institute of Neurological Disorders and Stroke, narcolepsy is the third most frequently diagnosed primary sleep disorder found in patients who seek treatment at sleep clinics, after obstructive sleep apnea and restless legs syndrome. (10) Cataplexy is present in about 70% of patients with narcolepsy, whereas sleep paralysis (30% to 50%) and hypnagogic hallucinations (20% to 40%) are experienced less often all 4 symptoms are present in an estimated 11% to 14% of patients with narcolepsy. (8,10,11)ĮDS is the symptom that is experienced by almost all patients with narcolepsy. (8,9) Its 4 classic symptoms are EDS, cataplexy (a sudden drop in muscle tone that is triggered by emotional factors), sleep paralysis (a generalized flaccid paralysis that happens slightly before or at the time of falling asleep or on awakening), and hypnagogic hallucinations (hallucinations that occur while falling asleep). Narcolepsy is a chronic, neurologic sleep disorder that results from the dysregulation of sleep-wake cycles. Differential diagnosis of narcolepsy and current treatment options will be discussed. This supplement uses a case-based approach to describe the underlying pathology and symptoms of narcolepsy. (6,7) Narcolepsy was found to cause some of the highest measures of excessive sleepiness (FIGURE 1). (5) The effects of some of these sleep disorders and other chronic illnesses on daytime sleepiness are measured using the Epworth Sleepiness Scale (ESS TABLE 1). Hypersomnia can result from several primary sleep disorders, including narcolepsy, sleep apnea, restless legs syndrome, idiopathic hypersomnia, and periodic limb movement disorder. (3,4) In contrast, hypersomnia refers to difficulty in staying awake and is characterized by recurrent episodes of excessive daytime sleepiness (EDS) or prolonged nighttime sleep. Insomnia results from disorders that cause difficulty with falling asleep and staying asleep examples are hyperarousal, circadian dysrhythmia, and homeostatic dysregulation. (2) Most of these disorders can be classified as causing insomnia and/or hypersomnia. Currently, 88 sleep disorders are listed in the International Classification of Sleep Disorders, as established by the American Academy of Sleep Medicine, and sleep disorders adversely affect more than an estimated 70 million Americans. Sleepiness and disrupted sleep can result from a large number of pathological disorders. ![]() Mood, attention, and behavior deteriorate. (1) When sleep is disrupted for more than a short time, normal daily functions decline. Sleep is a physiologic state that performs an essential restorative function and facilitates learning and memory consolidation. ![]()
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